Natural products: Hunting microbial metabolites.
نویسنده
چکیده
منابع مشابه
Introduction of new tools for chemical biology research on microbial metabolites.
Recently, high-throughput screening (HTS) has become the mainstream technique for drug discovery. Compounds that are synthesized by combinatorial chemistry might be more suitable than natural products to apply to HTS, because the purification procedure is a drawback of using natural products. Nevertheless, natural products remain an extremely important source of drugs. To overcome the demerits ...
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Marine animals and plants such as sponges, sea squirts, corals, worms and algae host diverse and abundant symbiotic microorganisms. Marine microbial symbionts are possible the true producers or take part in the biosynthesis of some bioactive marine natural products isolated from the marine organism hosts. Investigation of the pharmaceutical metabolites may reveal the biosynthesis mechanisms of ...
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ورودعنوان ژورنال:
- Nature chemistry
دوره 7 5 شماره
صفحات -
تاریخ انتشار 2015